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Dihydroartemisinin increased the abundance of by YAP1 depression that sensitizes hepatocellular carcinoma to anti-PD-1 immunotherapy

Frontiers of Medicine 2023, Volume 17, Issue 4,   Pages 729-746 doi: 10.1007/s11684-022-0978-2

Abstract: Mechanistically, hepatocyte-specific Yap1 knockout (Yap1LKO) maintained bileacid homeostasis in the liver, resulting in an increased abundance of A. muciniphila in the colon

Keywords： hepatocellular carcinoma     YAP1     Akkermansia muciniphila     anti-PD-1     dihydroartemisinin     bile acid    

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Bile duct injury repair — earlier is not better

Vinay K. Kapoor

Frontiers of Medicine 2015, Volume 9, Issue 4,   Pages 508-511 doi: 10.1007/s11684-015-0418-7

Abstract:

Bile duct injury is a common complication of cholecystectomy.The timing of bile duct injury repair remains controversial.Most patients with bile duct injury present with bile leak and sepsis; thus, early repair is not recommendedPercutaneous drainage of bile and endoscopic stenting are the mainstays of treatment of bile leak becausethey convert acute bile duct injury into a controlled external biliary fistula.

Keywords： bile duct injury     cholecystectomy     laparoscopic cholecystectomy    

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Bile acids and their effects on diabetes

Cynthia Rajani, Wei Jia

Frontiers of Medicine 2018, Volume 12, Issue 6,   Pages 608-623 doi: 10.1007/s11684-018-0644-x

Abstract: Manipulation of bile acid (BA) receptors and the BA pool have been shown to be useful in establishing

Keywords： bile acids     metabolic memory     diabetes     circadian rhythm     bariatric surgery    

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Strategies of minimally invasive treatment for intrahepatic and extrahepatic bile duct stones

Zongming Zhang, Zhuo Liu, Limin Liu, Mengmeng Song, Chong Zhang, Hongwei Yu, Baijiang Wan, Mingwen Zhu, Zixu Liu, Hai Deng, Haiming Yuan, Haiyan Yang, Wenping Wei, Yue Zhao

Frontiers of Medicine 2017, Volume 11, Issue 4,   Pages 576-589 doi: 10.1007/s11684-017-0536-5

Abstract: method, effect, and complications of minimally invasive treatment of intrahepatic and extrahepatic bileduct stones by combining our practical experience were summarized as follows. (1) For intrahepatic bileduct stones, the operation may be selected by laparoscopic liver resection, laparoscopic common bilesphincterotomy (EST) or endoscopic papillary balloon dilatation, LC plus laparoscopic transcystic common bileplus LCBDE, and T-tube drainage or primary suture. (3) For concomitant intrahepatic and extrahepatic bile

Keywords： laparoscopy     choledochoscopy     duodenoscopy     cholelithiasis     minimally invasive treatment    

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Artificial Bear Bile: A Novel Approach to Balancing Medical Requirements and Animal Welfare

Yong Li,Yuhong Huang,Nan Feng,Heping Zhang,Jing Qu,Shuanggang Ma,Yunbao Liu,Jiang Li,Shaofeng Xu,Ling Wang,Mi Zhang,Jie Cai,Weiping Wang,Ru Feng,Hang Yu,Bo Yu,Dailiang Liang,Heping Qin,Suxiang Luo,Yanfen Li,

Engineering doi: 10.1016/j.eng.2023.09.017

Abstract: Bear bile has been a valuable and effective medicinal material in traditional Chinese medicine (TCM)Here, we present a new approach for creating artificial bear bile (ABB) as a high-quality and sustainablealternative to natural bear bile.This study addresses the scientific challenges of creating bear bile alternatives through interdisciplinarytechnologies, our research has achieved the environmentally friendly, large-scale production of bear bile

Keywords： Artificial bear bile     Chemical profile     Formula optimization     Pharmacodynamic consistency     Preclinical toxicological    

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A mini review: Shape memory polymers for biomedical applications

Kaojin Wang, Satu Strandman, X. X. Zhu

Frontiers of Chemical Science and Engineering 2017, Volume 11, Issue 2,   Pages 143-153 doi: 10.1007/s11705-017-1632-4

Abstract: Shape memory polymers (SMPs) are smart materials that can change their shape in a pre-defined manner under a stimulus. The shape memory functionality has gained considerable interest for biomedical applications, which require materials that are biocompatible and sometimes biodegradable. There is a need for SMPs that are prepared from renewable sources to be used as substitutes for conventional SMPs. In this paper, advances in SMPs based on synthetic monomers and bio-compounds are discussed. Materials designed for biomedical applications are highlighted.

Keywords： shape memory polymer     biodegradability     biocompatibility     biomedical application     bile acids    

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Sulfonic acid-functionalized mesoporous silica catalyst with different morphology for biodiesel production

Frontiers of Chemical Science and Engineering 2022, Volume 16, Issue 8,   Pages 1198-1210 doi: 10.1007/s11705-021-2133-z

Abstract: Sulfonic acid functionalized mesoporous silica based solid acid catalysts with different morphology wereThe sulfonic acid functionalized mesoporous silica catalysts of spherical shape and the cube shape werecatalytic biodiesel production reaction over the catalysts were studied by esterification of free fatty acid, oleic acid with methanol.The effect of various reaction parameters such as catalyst concentration, acid/alcohol molar ratio, catalyst

Keywords： solid acid catalyst     mesoporous silica     sulfonic acid     biodiesel     esterification     oleic acid    

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Amino acid promoted hydrogen battery system using Mn-pincer complex for reversible CO hydrogenation toformic acid

Frontiers in Energy 2022, Volume 16, Issue 5,   Pages 697-699 doi: 10.1007/s11708-022-0843-7

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Enzyme@bismuth-ellagic acid: a versatile platform for enzyme immobilization with enhanced acid-base stability

Frontiers of Chemical Science and Engineering 2023, Volume 17, Issue 6,   Pages 784-794 doi: 10.1007/s11705-022-2278-4

Abstract: biocatalysts; however, it is limited by the conditions of metal–organic framework synthesis and its acid-baseHerein, a biocatalytic platform with improved acid-base stability was constructed via a one-pot methodusing bismuth-ellagic acid as the carrier.Bismuth-ellagic acid is a green phenol-based metal–organic framework whose organic precursor is extractedacid was enhanced, which remained stable over a wide pH range (2–12) and achieved multiple recycling

Keywords： bismuth-ellagic acid     in situ encapsulation     enzyme@MOF biocomposites    

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Discovery of novel ursolic acid derivatives as effective antimicrobial agents through a ROS-mediated

Frontiers of Chemical Science and Engineering 2023, Volume 17, Issue 12,   Pages 2101-2113 doi: 10.1007/s11705-023-2361-5

Abstract: In this study, we prepared three series of ursolic acid derivatives and assessed their antibacterialredox system of phytopathogenic bacteria, further demonstrating the unprecedented potential of ursolic acid

Keywords： ursolic acid     antibacterial activities     reactive oxygen species     apoptosis    

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Synergistic scale inhibition of polyaspartic acid composite with magnetic field

LIU Zhenfa, WANG Yanji, GAO Yuhua, ZHANG Lihui

Frontiers of Chemical Science and Engineering 2007, Volume 1, Issue 3,   Pages 261-265 doi: 10.1007/s11705-007-0047-z

Abstract: Polyaspartic acid (PASP) composite, a scale inhibitor, was prepared from PASP, itaconic acid–acrylicacid–acrylic ester (IA-AA-AE) terpolymer and 2-phosphonobutane- 1,2,4-tricarboxylic acid (PBTCA).

Keywords： synergism     magnetic     PBTCA     dynamic     acid–acrylic acid–acrylic    

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Abiotic association of phthalic acid esters with humic acid of a sludge landfill

Xiaoli CHAI, Yongxia HAO, Xin ZHAO, Guixiang LIU, Ying ZHU, Rong JI, Jun WU, Huanhuan TONG, Youcai ZHAO

Frontiers of Environmental Science & Engineering 2012, Volume 6, Issue 6,   Pages 778-783 doi: 10.1007/s11783-012-0434-7

Abstract: The abiotic association between phthalic acid esters (PAEs) and humic substances (HS) in sludge landfillthe abiotic association of two abundant PAEs (diethyl phthalate and di- -butyl phthalate) with humic acid

Keywords： abiotic association     phthalic acid esters (PAEs)     humic acid     sludge     landfill    

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New perspectives in free nitrous acid (FNA) uses for sustainable wastewater management

Frontiers of Environmental Science & Engineering 2023, Volume 18, Issue 2, doi: 10.1007/s11783-024-1786-5

Abstract:

● The historical development of free nitrous acid (FNA) technologies

Keywords： Free nitrous acid     Acid-tolerant ammonia oxidizer     In situ generation     Wastewater management    

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Genomic and metabolomic analysis of with enhanced poly--glutamic acid production through atmospheric

Frontiers of Chemical Science and Engineering 2022, Volume 16, Issue 12,   Pages 1751-1760 doi: 10.1007/s11705-022-2211-x

Abstract: Poly-γ-glutamic acid is an extracellular polymeric substance with various applications owing toHowever, the ability of natural strains to produce poly-γ-glutamic acid is low.licheniformis CGMCC 2876, and a mutant strain M32 with an 11% increase in poly-γ-glutamic acidplipastatin synthase subunit C and glutamate, which might contribute to the higher poly-γ-glutamic acidThe maximum poly-γ-glutamic acid yield of 14.08 g·L–1 was finally reached with 30 g

Keywords： ARTP mutagenesis     Bacillus licheniformis     poly-γ-glutamic acid     metabolomics    

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Proline-2′-deoxymugineic acid, a phytosiderophore analog, drives beneficial rhizobacterial community

Frontiers of Agricultural Science and Engineering doi: 10.15302/J-FASE-2023531

Abstract:

● Proline-2′-deoxymugineic (PDMA) significantly altered the bacterial community in the peanut rhizosphere.

Keywords： rhizobacteria recruitment     peanut     plant-soil micronutrition enhancement     proline-2′-deoxymugineic acid    

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Title Author Date Type Operation

Dihydroartemisinin increased the abundance of by YAP1 depression that sensitizes hepatocellular carcinoma to anti-PD-1 immunotherapy

Journal Article

Bile duct injury repair — earlier is not better

Vinay K. Kapoor

Journal Article

Bile acids and their effects on diabetes

Cynthia Rajani, Wei Jia

Journal Article

Strategies of minimally invasive treatment for intrahepatic and extrahepatic bile duct stones

Zongming Zhang, Zhuo Liu, Limin Liu, Mengmeng Song, Chong Zhang, Hongwei Yu, Baijiang Wan, Mingwen Zhu, Zixu Liu, Hai Deng, Haiming Yuan, Haiyan Yang, Wenping Wei, Yue Zhao

Journal Article

Artificial Bear Bile: A Novel Approach to Balancing Medical Requirements and Animal Welfare

Yong Li,Yuhong Huang,Nan Feng,Heping Zhang,Jing Qu,Shuanggang Ma,Yunbao Liu,Jiang Li,Shaofeng Xu,Ling Wang,Mi Zhang,Jie Cai,Weiping Wang,Ru Feng,Hang Yu,Bo Yu,Dailiang Liang,Heping Qin,Suxiang Luo,Yanfen Li,

Journal Article

A mini review: Shape memory polymers for biomedical applications

Kaojin Wang, Satu Strandman, X. X. Zhu

Journal Article

Sulfonic acid-functionalized mesoporous silica catalyst with different morphology for biodiesel production

Journal Article

Amino acid promoted hydrogen battery system using Mn-pincer complex for reversible CO hydrogenation toformic acid

Journal Article

Enzyme@bismuth-ellagic acid: a versatile platform for enzyme immobilization with enhanced acid-base stability

Journal Article

Discovery of novel ursolic acid derivatives as effective antimicrobial agents through a ROS-mediated

Journal Article

Synergistic scale inhibition of polyaspartic acid composite with magnetic field

LIU Zhenfa, WANG Yanji, GAO Yuhua, ZHANG Lihui

Journal Article

Abiotic association of phthalic acid esters with humic acid of a sludge landfill

Xiaoli CHAI, Yongxia HAO, Xin ZHAO, Guixiang LIU, Ying ZHU, Rong JI, Jun WU, Huanhuan TONG, Youcai ZHAO

Journal Article

New perspectives in free nitrous acid (FNA) uses for sustainable wastewater management

Journal Article

Genomic and metabolomic analysis of with enhanced poly--glutamic acid production through atmospheric

Journal Article

Proline-2′-deoxymugineic acid, a phytosiderophore analog, drives beneficial rhizobacterial community

Journal Article